MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Clinical trials for MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE explained in plain language.
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Promising nerve pain drug trial for MGUS patients withdrawn before start
Disease control TerminatedThis study aimed to test if daratumumab could improve nerve damage (peripheral neuropathy) in people with a blood condition called MGUS. Participants would have received weekly injections for two months, then biweekly for four more months. However, the trial was withdrawn before …
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: PHASE2 • Sponsor: Georgetown University • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Diabetes drug metformin tested to stop blood cancer before it starts
Prevention OngoingThis study tests whether metformin, a widely used diabetes medicine, can stop early blood conditions (MGUS and smoldering myeloma) from turning into multiple myeloma. About 60 people with higher-risk MGUS or low-risk smoldering myeloma will receive either metformin or a placebo p…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Prevention
Last updated May 26, 2026 05:29 UTC
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Plant-Based diet trial aims to stop precancerous blood condition from turning into multiple myeloma
Prevention OngoingThis study tests whether a plant-based diet is practical for overweight people with MGUS or smoldering multiple myeloma, two early blood conditions that can lead to multiple myeloma. Over 12 weeks, 23 participants will follow a whole-food, plant-based diet to see if they can stic…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Prevention
Last updated May 26, 2026 05:27 UTC
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Massive MGUS screening aims to unlock myeloma mysteries
Knowledge-focused ENROLLING_BY_INVITATIONThis study screens 1000 adults aged 40 and older for MGUS, a condition with an abnormal blood protein that can sometimes lead to multiple myeloma. Researchers at Mayo Clinic will use advanced testing to find MGUS across diverse groups in Minnesota. The goal is to learn more about…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 05:21 UTC
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Iceland launches massive screening study to detect cancer risk before it starts
Knowledge-focused OngoingThis study is testing whether screening healthy people for a condition called MGUS can help find multiple myeloma earlier. Over 80,000 adults in Iceland were invited to participate. The goal is to see if early detection leads to better survival and fewer complications.
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: NA • Sponsor: University of Iceland • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC