METASTATIC SOFT-TISSUE SARCOMA

This study is testing whether adding a new drug called lurbinectedin to a standard chemotherapy (doxorubicin) works better than the standard drug alone for people with advanced leiomyosarcoma, a type of soft-tissue cancer. The first part of the study aims to find the safest dose …

This study is testing a new combination of two drugs, HDM201 and pazopanib, for people with advanced soft tissue sarcoma that has spread and stopped responding to standard chemotherapy. The first part aims to find the safest dose of the combination. The second part will gather ea…

This study is testing if combining three different cancer drugs works better than standard care for advanced soft tissue sarcoma that has spread. It will involve about 105 adults whose cancer has worsened after one or two prior treatments. The goal is to see if this combination c…

This early-stage trial is testing four different combinations of experimental drugs with existing cancer medications for people with metastatic solid tumors. The study aims to find safe doses and see if these combinations can shrink tumors in seven specific cancer types. It's des…

This study is testing whether combining two drugs, cabozantinib and temozolomide, can better control advanced soft tissue sarcomas that cannot be removed by surgery or have spread. The trial aims to see if this combination can stop the cancer from growing for longer and improve s…

This study is testing if a three-drug combination works better than a two-drug immunotherapy approach to control advanced soft tissue sarcoma. It will involve about 66 adults with specific types of sarcoma that have spread or cannot be surgically removed. The goal is to see if ad…