New drug combo shows promise for rare sarcomas

NCT ID NCT04200443

Ongoing Disease control Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Jan 05, 2026 · Last updated Apr 30, 2026 · Updated 19 times

Summary

This study tests two drugs, cabozantinib and temozolomide, in people with soft tissue sarcomas that cannot be surgically removed or have spread. The goal is to see if the combination can stop or slow tumor growth. About 72 adults with leiomyosarcoma or other sarcomas will participate.

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Contacts and locations

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Locations

City of Hope Medical Center

Duarte, California, 91010, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Northwestern University

Chicago, Illinois, 60611, United States
University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States

Conditions

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