METASTATIC GASTRIC CARCINOMA

This study is testing whether the drug talazoparib can help control advanced cancers in patients whose tumors have specific genetic mutations that affect how cells repair damaged DNA. The trial will enroll about 36 adults with various advanced solid tumors (like breast, ovarian, …

This is the first study in people to test a new oral medication called NKT3964. The main goals are to find a safe dose and see if the drug shows early signs of shrinking tumors in adults with advanced cancers that have spread and no longer respond to standard treatments. The stud…

This early-stage study is testing whether adding a drug called aldesleukin directly into the abdomen, along with standard immunotherapy and chemotherapy, can better treat stomach cancer that has spread to the abdominal lining. The goal is to see if this combination can shrink the…

This early-stage study is testing the safety and best dose of a new two-drug combination for people with advanced solid tumors that have a specific marker called HER2. The treatment pairs an existing targeted cancer drug with a new pill that aims to block cancer cells' ability to…

This study is for people with advanced gastrointestinal cancers that have spread and have stopped responding to immunotherapy. Researchers want to see if giving a short, targeted course of radiation to one tumor can 'wake up' the body's immune system to attack all the cancer, inc…

This study is testing a new combination of five different treatments for people with advanced stomach or esophageal cancer that has worsened after one prior therapy. The goal is to see if this multi-drug approach can better control the cancer. The treatment includes two immunothe…

This early-stage study is testing the safety of a new, minimally invasive procedure called PIPAC. It delivers chemotherapy as a fine mist directly into the abdomen for people with advanced ovarian, uterine, stomach, colon, or appendix cancers that have spread to the abdominal lin…

This early-stage study is testing the safety and best dose of a new two-drug combination for people with advanced cancers that have a specific marker called HER2. The trial focuses on stomach and gastroesophageal junction cancers that have spread or cannot be removed by surgery, …

This study aims to learn more about the tiny blood vessels that feed solid tumors. Researchers will use a special microscope during a patient's standard cancer surgery to see these vessels in real time. The goal is to understand how tumor blood flow works and if it relates to how…