Metastatic colorectal carcinoma
Clinical trials for Metastatic colorectal carcinoma explained in plain language.
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Can a new drug combo revive the immune System's attack on resistant cancers?
Disease control CompletedThis phase 2 trial tests whether adding an experimental drug called pixatimod to the immunotherapy nivolumab can shrink tumors in people with advanced melanoma, non-small cell lung cancer, or colorectal cancer that has stopped responding to prior treatment. One group with colorec…
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase 2 • Sponsor: Diwakar Davar • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New cocktail of drugs shows promise for tough colorectal cancer
Disease control CompletedThis phase 1 trial tested a combination of regorafenib (a targeted therapy) plus two immunotherapy drugs (nivolumab and ipilimumab) in 39 patients with advanced colorectal cancer that had spread and stopped responding to chemotherapy. The goal was to find the safest dose and chec…
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New cocktail of drugs shows promise for Tough-to-Treat colon cancer
Disease control CompletedThis early-phase trial tested a combination of three drugs—utomilumab, cetuximab, and irinotecan—in 34 patients with advanced colorectal cancer that had spread and stopped responding to standard treatment. The goal was to find the safest dose and check for side effects. While the…
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC