METASTATIC COLORECTAL ADENOCARCINOMA
Clinical trials for METASTATIC COLORECTAL ADENOCARCINOMA explained in plain language.
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Stool transplant may help immunotherapy work in Hard-to-Treat colorectal cancer
Disease control OngoingThis study tests whether giving a fecal (stool) transplant along with re-starting immunotherapy (pembrolizumab or nivolumab) can help control metastatic colorectal cancer in people whose tumors did not respond to immunotherapy alone. The trial enrolls 15 adults with advanced colo…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 07:03 UTC
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New hope for hard-to-treat colorectal cancer? early trial combines three drugs
Disease control TerminatedThis early-phase study tests whether adding a new drug (ZEN003694) to two approved cancer drugs (cetuximab and encorafenib) is safe and effective for people with a specific type of advanced colorectal cancer (BRAF V600E) that has stopped responding to standard treatments. About 3…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 06:46 UTC
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New hope for Tough-to-Treat colorectal cancer: immun combo vs single drug
Disease control OngoingThis study tests whether a combination of chemotherapy, a blood vessel blocker (bevacizumab), and an immunotherapy drug (atezolizumab) works better than atezolizumab alone for people with a specific genetic type of advanced colorectal cancer (dMMR/MSI-H) that has spread. About 12…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 06:46 UTC
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New hope for tough colorectal cancer: drug combo trial targets resistant tumors
Disease control OngoingThis study tests two drugs, panitumumab and trametinib, in people with stage IV colorectal cancer that no longer responds to standard treatments. The goal is to see if these drugs can shrink tumors or slow the cancer's growth. About 59 participants will receive either panitumumab…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New combo therapy offers hope for hard-to-treat colorectal cancer
Disease control OngoingThis early-stage trial tests a combination of chemotherapy (FOLFOX), a blood vessel blocker (bevacizumab), and two immunotherapy drugs (botensilimab and balstilimab) in 20 people with a type of advanced colorectal cancer (MSS) that has spread. The goal is to find the safest dose …
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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New cocktail aims to outsmart Chemo-Resistant colorectal cancer
Disease control OngoingThis study tests a combination of three drugs (botensilimab, balstilimab, and regorafenib) in people with a type of colorectal cancer that has spread and stopped responding to chemotherapy. The goal is to see if this mix can shrink tumors or slow the disease. About 28 adults with…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 19, 2026 11:59 UTC