MEDULLOBLASTOMA RECURRENT
Clinical trials for MEDULLOBLASTOMA RECURRENT explained in plain language.
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New hope for kids with brain cancer: triple therapy trial launches
Disease control Recruiting nowThis early-phase study tests a new drug (SGT-53) combined with radiation and immunotherapy (Nivolumab) for children whose brain tumors have returned or not responded to standard treatments. The goal is to find a safe dose and understand side effects. Up to 18 children with specif…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: EARLY_PHASE1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated May 26, 2026 11:28 UTC
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New hope for kids with recurring brain tumors: low-dose combo therapy aims to buy time
Disease control Recruiting nowThis study tests a combination of low-dose chemotherapy and targeted drugs to slow tumor growth in children whose brain cancers have returned. The goal is to extend survival while maintaining a good quality of life. About 232 children with recurrent medulloblastoma, ependymoma, A…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE2 • Sponsor: Medical University of Vienna • Aim: Disease control
Last updated May 26, 2026 11:23 UTC
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Virus therapy takes on childhood brain cancer
Disease control Recruiting nowThis early-stage trial tests a specially engineered virus, G207, in children and young adults (ages 3 to 21) whose cerebellar brain tumors have come back or not responded to standard treatments. The virus is injected directly into the tumor, and a single low dose of radiation is …
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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Promising combo therapy for childhood cancers enters human trials
Disease control Recruiting nowThis study tests a combination of two drugs—Lutathera (a targeted radiation therapy) and olaparib (a PARP inhibitor)—in children and teens aged 3 to 18 with solid tumors that have come back or not responded to standard treatment. The goal is to find the safest dose and see if the…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1, PHASE2 • Sponsor: Fundación de investigación HM • Aim: Disease control
Last updated May 18, 2026 12:00 UTC
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Brain tumor biobank aims to unlock secrets of rare genetic mutation
Knowledge-focused Recruiting nowThis study is creating a biobank for children and adults with a relapsed or hard-to-treat type of brain tumor called sonic hedgehog medulloblastoma that has a specific genetic change (U1 mutation). Researchers will collect medical records, tumor samples, and optional cheek swabs …
Matched conditions: MEDULLOBLASTOMA RECURRENT
Sponsor: Mohammad H. Abu Arja • Aim: Knowledge-focused
Last updated May 26, 2026 11:26 UTC
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Tailored tumor testing aims to match kids with best drugs
Knowledge-focused Recruiting nowThis study tests a new approach for children and young adults whose medulloblastoma or ependymoma has come back. Doctors will analyze the tumor's genes and test drugs on it in real time to create a personalized treatment plan. The goal is to see if this can be done quickly enough…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC