MALIGNANCY

This study looks at two ways to rebuild the chest wall after removing a tumor or infected tissue. One method uses a special bone cement, and the other uses twisted stainless steel wires, which are cheaper and more flexible. Researchers want to see which approach causes less pain,…

This study tests atezolizumab, a drug already approved for some cancers, in people with rare cancers that have high tumor mutational burden (TMB), high microsatellite instability (MSI), or a specific DNA repair defect (CMMRD). About 30 adults, teens, and children will receive the…

This study tests a drug called entrectinib, already approved for some lung cancers, in people with rare cancers that have a specific genetic change (ROS1 fusion). About 30 adults and children with these rare tumors will receive the drug. Researchers will measure if tumors shrink …

This study tests capmatinib, a drug already approved for certain lung cancers, in adults with other rare cancers that have specific MET gene changes. About 30 participants will receive the drug to see if their tumors shrink or stop growing for at least 24 weeks. The goal is to fi…

This study aims to improve how doctors see digestive system cancers (like liver, stomach, and pancreatic cancer) using special PET/CT imaging probes. Researchers will test these probes in 400 adults to measure how they spread in the body and how well they find tumors. The goal is…

This study collects blood, tissue, and health data from 240 cancer patients who have had serious side effects from immunotherapy. The goal is to store these samples in a national biorepository for future research. This will help scientists better understand, predict, and prevent …

This study looks at whether repeated hyperbaric oxygen therapy (HBOT) can damage DNA in people who have had radiation for cancer. HBOT uses high-pressure oxygen to help heal damaged tissues, but it may also create harmful molecules that could increase cancer risk. Researchers wil…