MALARIA,FALCIPARUM

This early-stage study tested the safety and immune response of a new malaria vaccine candidate. It involved 66 healthy adults from Europe and Africa, some with prior exposure to malaria. Volunteers received three shots of the experimental vaccine with different immune-boosting a…

This study tested whether finding and treating very low-level malaria infections in children leads to better long-term health, growth, and development. It involved 600 children in Tanzania, comparing standard care to two methods using more sensitive tests to detect these hidden i…

This study tested a lab-made antibody called TB31F to see if it could safely help stop the spread of malaria. Researchers in Mali gave the antibody to 167 adults and children who are regularly exposed to malaria to check for side effects and to see if it reduced the chance of mos…

This study tested a new oral drug, MMV367, for malaria. Researchers gave healthy volunteers a small, controlled dose of malaria parasites and then gave them the drug to see how their bodies processed it and how well it fought the infection. The main goal was to understand the rel…

This study tested whether rotating different first-line malaria drugs across clinics in western Kenya could slow down the parasites from becoming resistant to treatment. Researchers also checked if local health systems could practically manage this rotation strategy. They tracked…

This study is the first time a new long-acting injection for malaria is being tested in people. Its main goal is to check if the injection is safe and how the body handles it. The study involves 24 healthy volunteers who receive a single shot at one of three increasing doses or a…