Lupus nephritis (LN)
Clinical trials for Lupus nephritis (LN) explained in plain language.
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Engineered immune cells take on lupus kidney disease in early trial
Disease control CancelledThis early-phase study tests a new treatment called C-CAR168 for people with lupus nephritis that hasn't improved with standard therapies. C-CAR168 is made from a patient's own immune cells, which are modified to target and attack faulty immune cells. The study will enroll 24 adu…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase 1/2 • Sponsor: AbelZeta Inc. • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Could a diabetes drug shield kidneys from lupus damage?
Disease control OngoingThis phase 2 trial tests whether dapagliflozin, a drug already used for diabetes and chronic kidney disease, can slow kidney damage in people with lupus nephritis. Lupus nephritis is a serious complication of lupus that causes kidney inflammation and can lead to chronic kidney di…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase 1/2 • Sponsor: Hospital Civil Juan I. Menchaca • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Kidney biopsies probed for scarring signal in lupus
Knowledge-focused OngoingResearchers at Ain Shams University are examining kidney biopsy tissue from 30 adults with lupus nephritis to see whether a protein called TGF-beta is present and how it relates to kidney scarring, disease activity, and chronic damage. Participants undergo a standard ultrasound-g…
Matched conditions: LUPUS NEPHRITIS (LN)
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC