LUPUS NEPHRITIS (LN)
Clinical trials for LUPUS NEPHRITIS (LN) explained in plain language.
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Engineered immune cells take aim at lupus in first human trial
Disease control Not yet recruitingThis early-stage trial tests a new treatment made from a patient's own immune cells, modified to target and destroy faulty cells that cause lupus. It is for 20 people aged 16-70 whose lupus has not improved with at least two standard treatments. The goal is to see if it is safe a…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: PHASE1, PHASE2 • Sponsor: iCell Gene Therapeutics • Aim: Disease control
Last updated May 26, 2026 09:02 UTC
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New drug trial hopes to tame autoimmune attacks in lupus and MS
Disease control Not yet recruitingThis study tests a new medicine called MTM-H-001 in 75 adults with B-cell-related autoimmune diseases such as lupus, multiple sclerosis, and rheumatoid arthritis. The goal is to see if the drug is safe and can help control disease activity. Participants will receive the drug and …
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: NA • Sponsor: Beijing GoBroad Hospital • Aim: Disease control
Last updated May 26, 2026 09:01 UTC
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Could a diabetes pill protect kidneys in lupus patients?
Disease control Not yet recruitingThis study tests whether dapagliflozin, a drug already used for diabetes and other kidney diseases, can help people with lupus nephritis—a serious kidney condition caused by lupus. About 33 adults with early active lupus nephritis will receive either dapagliflozin or a placebo al…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 26, 2026 09:01 UTC
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Experimental CAR-T therapy takes on tough lupus kidney cases
Disease control Not yet recruitingThis study tests a new treatment called CRC01 for people with severe lupus that has caused kidney damage (lupus nephritis). CRC01 is made from the patient's own immune cells, which are modified to target and calm the overactive immune system. The trial will enroll 39 adults who h…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: PHASE1, PHASE2 • Sponsor: Curocell Inc. • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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Engineered immune cells take aim at Hard-to-Treat kidney disease
Disease control Not yet recruitingThis early-stage study tests a new treatment for people with severe autoimmune kidney diseases (lupus nephritis, IgA nephropathy, or membranous nephropathy) that have not responded to standard therapies. The treatment uses specially engineered immune cells (CAR-γδ T cells) design…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: EARLY_PHASE1 • Sponsor: Air Force Military Medical University, China • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Engineered immune cells take aim at Hard-to-Treat lupus
Disease control Not yet recruitingThis early-stage trial tests a new treatment called C-CAR168 for people with lupus nephritis (kidney inflammation from lupus) that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified to target and destroy harmful cells involved in th…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: PHASE1, PHASE2 • Sponsor: AbelZeta Inc. • Aim: Disease control
Last updated May 20, 2026 11:57 UTC