LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Clinical trials for LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA explained in plain language.
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New electric cap fights pancreatic cancer alongside chemo
Disease control TEMPORARILY_NOT_AVAILABLEThis program offers adults with locally advanced pancreatic cancer access to a wearable device that delivers electric fields (TTFields) to the tumor area, combined with standard chemotherapy. The goal is to control the disease while the device is being reviewed by the FDA. Partic…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Sponsor: NovoCure GmbH • Aim: Disease control
Last updated May 26, 2026 09:03 UTC
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Targeted drug combo shows promise for genetic pancreatic cancer
Disease control OngoingThis study tests whether adding the drug veliparib to standard chemotherapy (gemcitabine and cisplatin) works better than chemotherapy alone for people with advanced pancreatic cancer who have a BRCA or PALB2 gene mutation. About 83 participants will receive either the combinatio…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 09:00 UTC
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Experimental vaccine targets Hard-to-Treat pancreatic tumors
Disease control OngoingThis early-phase study tested a special vaccine (PANVAC) given directly into the tumor plus under the skin, along with a drug that boosts immune cells (sargramostim), in 18 people with advanced pancreatic cancer that could not be removed by surgery. The main goal was to find the …
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New drug cocktail aims to starve pancreatic tumors
Disease control OngoingThis early-phase study tests a combination of two drugs—calaspargase pegol-mknl and cobimetinib—in people with advanced pancreatic cancer that has spread. The goal is to find the safest dose and see if the combo can control the disease by cutting off the cancer cells' food supply…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Can chemo shrink pancreatic tumors enough for safe surgery?
Disease control OngoingThis study looks at whether giving chemotherapy before surgery can make advanced pancreatic tumors small enough to be safely removed. It involves 2 people with locally advanced pancreatic cancer that cannot be operated on initially. The goal is to see if this approach leads to co…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated May 18, 2026 12:00 UTC
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New scan could reveal hidden oxygen starvation in pancreatic cancer
Knowledge-focused OngoingThis study aims to see if a special PET-MRI scan using a tracer called FAZA can measure low oxygen (hypoxia) in pancreatic tumors. About 20 people with advanced pancreatic cancer that cannot be removed by surgery will get the scan before and after their standard radiation treatme…
Matched conditions: LOCALLY ADVANCED PANCREATIC ADENOCARCINOMA
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC