Locally advanced gastroesophageal junction adenocarcinoma
Clinical trials for Locally advanced gastroesophageal junction adenocarcinoma explained in plain language.
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Dual immunotherapy plus chemo before surgery: a new way to shrink stomach tumors?
Disease control Not yet recruitingResearchers are testing whether combining an experimental dual immunotherapy drug called QL1706 with standard chemotherapy (docetaxel, oxaliplatin and S-1) before surgery can help patients with locally advanced gastric or gastroesophageal junction cancer. The study enrolls 34 adu…
Matched conditions: LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase 2 • Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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New drug cocktail aims to fight Hard-to-Treat stomach cancers
Disease control Not yet recruitingThis early-phase trial tests whether adding the experimental drug futibatinib to standard chemotherapy (paclitaxel) and an antibody (ramucirumab) is safe for people with advanced stomach, gastroesophageal junction, or esophageal cancer that cannot be removed by surgery. The study…
Matched conditions: LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase 1 • Sponsor: Northwestern University • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Stomach cancer hope: triple therapy may boost tumor clearance before surgery
Disease control Not yet recruitingThis phase II trial tests whether adding low-dose radiotherapy and the immunotherapy drug tislelizumab to standard chemotherapy can improve outcomes for people with locally advanced stomach or gastroesophageal junction cancer. About 114 participants will be randomly assigned to r…
Matched conditions: LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase 2 • Sponsor: Jiangsu Cancer Institute & Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New hope for stomach cancer: drug combo aims to wipe out tumors before surgery
Disease control Not yet recruitingThis study tests whether adding the drug ivonescimab to standard chemotherapy (SOX) can better shrink or eliminate tumors in people with locally advanced stomach or gastroesophageal junction cancer before surgery. About 154 adults aged 18-75 will be randomly assigned to receive e…
Matched conditions: LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase 2 • Sponsor: Sichuan University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC