Locally advanced gastric adenocarcinoma
Clinical trials for Locally advanced gastric adenocarcinoma explained in plain language.
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Can immunotherapy wipe out stomach cancer before surgery?
Cure PausedThis trial tests whether giving immunotherapy drugs before surgery can completely eliminate tumors in patients with a specific type of stomach or gastro-esophageal junction cancer that has a high number of genetic mutations. Participants will receive either one drug (zimberelimab…
Matched conditions: LOCALLY ADVANCED GASTRIC ADENOCARCINOMA
Phase 2 • Sponsor: Royal Marsden NHS Foundation Trust • Aim: Cure
Last updated Aug 23, 2026 00:00 UTC
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Experimental drug duo targets Hard-to-Treat cancers
Disease control OngoingThis early-phase trial tests two drugs together—sonidegib and pembrolizumab—in 36 adults with advanced solid tumors that have spread. Sonidegib blocks a growth signal in cancer cells, while pembrolizumab helps the immune system attack the tumor. The main goals are to find the saf…
Matched conditions: LOCALLY ADVANCED GASTRIC ADENOCARCINOMA
Phase 1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New study aims to improve survival in advanced stomach cancer
Knowledge-focused OngoingThis study looks back at 300 people with advanced stomach or gastroesophageal junction cancer to see how different treatments before and after surgery affect survival. The goal is to find out which treatment plans work best and whether tumor shrinkage after pre-surgery therapy pr…
Matched conditions: LOCALLY ADVANCED GASTRIC ADENOCARCINOMA
Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC