LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Clinical trials for LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA explained in plain language.
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New drug trio aims to tame tough cancers
Disease control OngoingThis study is testing a combination of three immunotherapy drugs—tocilizumab, ipilimumab, and nivolumab—in people with advanced melanoma, non-small cell lung cancer, or bladder cancer. The main goals are to see if adding tocilizumab is safe and if it helps the other two drugs wor…
Matched conditions: LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 04, 2026 06:51 UTC
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New combo therapy trial offers hope for Tough-to-Treat bladder cancer
Disease control OngoingThis study is testing whether adding a chemotherapy drug (eribulin) to an immunotherapy drug (atezolizumab) works better than the immunotherapy drug alone for people with advanced bladder cancer that has spread or come back. It is for patients who cannot take a standard chemother…
Matched conditions: LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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New drug duo aims to attack tough bladder cancer
Disease control OngoingThis early-phase trial is testing the safety and best dose of a two-drug combination for people with advanced bladder cancer that has spread and has specific genetic changes (FGFR2/3). The study is for patients whose cancer has continued to grow despite trying standard chemothera…
Matched conditions: LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Personalized cancer fight: matching drugs to your Tumor's genetic fingerprint
Disease control OngoingThis study is testing whether specific genetic markers in a patient's tumor can predict if they will respond well to immunotherapy drugs. It is for people with advanced bladder cancer that has spread and has stopped responding to standard chemotherapy. Participants receive two im…
Matched conditions: LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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Heart drug joins fight against bladder cancer
Disease control OngoingThis study is testing if adding a common, low-cost blood pressure medication called propranolol to standard immunotherapy helps people with advanced bladder cancer. Six participants will receive either immunotherapy alone or immunotherapy plus propranolol. The main goal is to see…
Matched conditions: LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Cancer trial asks: can patients stop treatment sooner and stay well?
Disease control OngoingThis study is for people with advanced bladder cancer who have already had about a year of immunotherapy. It compares two approaches: continuing the immunotherapy treatment versus stopping it. The main goal is to see if stopping treatment leads to similar survival rates while pot…
Matched conditions: LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New pill targets genetic weakness in Tough-to-Treat bladder cancers
Disease control OngoingThis study is testing an oral drug called sapanisertib for people with advanced bladder cancer that has a specific genetic mutation (TSC1 or TSC2) and has stopped responding to standard platinum-based chemotherapy. The goal is to see if the drug can shrink tumors and control the …
Matched conditions: LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Major trial tests Immune-Boosting drug to stop aggressive bladder cancer from coming back
Disease control OngoingThis large study is testing whether a drug called pembrolizumab can help prevent cancer from returning in people who have had surgery for muscle-invasive bladder or upper urinary tract cancer. After surgery, participants are randomly assigned to either receive the drug (which hel…
Matched conditions: LOCALLY ADVANCED BLADDER UROTHELIAL CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC