LIVER METASTASES

This study tests a combination of two drugs, atezolizumab and bevacizumab, in people with liver cancer or lung cancer that has spread to the liver. The goal is to see how long the cancer stays under control. Researchers will collect blood and tumor samples to understand how the d…

This study compares two treatments—microwave ablation and stereotactic body radiation therapy—for colorectal cancer that has spread to the liver in 100 patients. The goal is to see which method better controls tumor growth with fewer side effects. Participants have 1 to 3 liver t…

This study tests a device that uses sound waves (histotripsy) to break apart liver tumors without needles or surgery. About 47 adults with liver cancer or tumors that spread to the liver will receive this treatment. The goal is to see if the device can safely and completely destr…

This study is for adults with colorectal cancer that has spread to the liver and who are scheduled for surgery to remove the liver tumors. The goal is to see if taking a study drug called QBECO (self-injected at home) before and after surgery can lower the chance of the cancer co…

This study tests a precise type of radiation called SBRT for people with liver cancer or tumors that spread to the liver from other cancers. About 280 adults who cannot join other trials will receive SBRT. The goal is to see how well it controls tumor growth and what side effects…

This study tests a device that uses sound waves (histotripsy) to break apart liver tumors without cutting into the body. About 24 adults with liver cancer or tumors that spread to the liver will receive this treatment. The goal is to see if the device can safely and completely de…

This study tests whether a special PET scan can predict if the drug T-DM1 will work in people with advanced HER2-positive breast cancer that has spread. Ten women with metastatic breast cancer received a radioactive tracer to see where the drug goes in the body. The goal is to he…

This study tests whether a low-radiation CT scan, enhanced with artificial intelligence software, can find liver tumors as accurately as a standard CT scan. About 146 adults with colorectal cancer that has spread to the liver will participate. The goal is to see if the new method…

This study looks at whether a home-based exercise program is practical and safe for people aged 65 and older who are waiting for liver or bile duct cancer surgery. About 25 participants will be asked to follow a moderate exercise routine and attend virtual training sessions. The …