Liver dysfunction
Clinical trials for Liver dysfunction explained in plain language.
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Liver health may change how this drug works
Knowledge-focused CompletedThis study looks at how lepodisiran enters the blood and leaves the body in people with mild, moderate, or severe liver problems compared to those with healthy livers. About 33 adults will receive a single injection under the skin. The goal is to understand how liver function aff…
Matched conditions: LIVER DYSFUNCTION
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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New diabetes drug tested in patients with liver issues
Knowledge-focused CompletedThis early-stage trial looked at how a single 50mg dose of pyroglutamate rongliflozin capsules behaves in 32 adults with mild or moderate liver damage and type 2 diabetes, compared to healthy volunteers. Researchers measured drug levels in the blood and tracked side effects to un…
Matched conditions: LIVER DYSFUNCTION
Phase 1 • Sponsor: Sunshine Lake Pharma Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Liver MRI could spot dangerous drug interactions early
Knowledge-focused CompletedThis study tested whether a special MRI scan can measure how two common drugs, metformin and ciclosporin, affect the liver. Twelve healthy volunteers received the MRI dye gadoxetate before and after taking the drugs. The goal was to see if the scan could detect changes in liver f…
Matched conditions: LIVER DYSFUNCTION
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Microscope or loupes? study tests better tool for liver transplant bile duct repair
Knowledge-focused CompletedThis study compared two surgical tools—surgical loupes (magnifying glasses) and a microscope—for repairing bile ducts during living donor liver transplants. 52 adults receiving a right-lobe liver graft with a single bile duct opening took part. The goal was to see which tool led …
Matched conditions: LIVER DYSFUNCTION
Sponsor: Istanbul Medipol University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC