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New MRI method could spot risky drug interactions early

NCT ID NCT07541807

First seen Apr 24, 2026 · Last updated May 21, 2026 · Updated 8 times

Summary

This study tested whether a special MRI scan can measure how two common drugs, metformin and ciclosporin, affect the liver's ability to process a contrast dye. Twelve healthy adults each had MRI scans before and after taking one of the drugs. The goal was to see if this imaging technique could become a safe, non-invasive tool for detecting drug-drug interactions early in development.

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Contacts and locations

Locations

  • Royal Hallamshire Hospital

    Sheffield, United Kingdom

  • University of Sheffield, POLARIS, 18 Claremont Crescent

    Sheffield, S10 2RX, United Kingdom

Conditions

Explore the condition pages connected to this study.