LIPOSARCOMA

This early-phase trial tests the safety and best dose of the chemotherapy drug eribulin when given with radiation before surgery for a rare cancer called retroperitoneal liposarcoma. About 15 adults with this abdominal fat-cell tumor will receive the combination to see how well i…

This early-phase study tests a new treatment called CATCH T cells for people with certain solid tumors (like liver cancer) that have come back or not responded to standard care. The treatment involves taking a patient's own immune cells, adding special genes to help them recogniz…

This early-stage trial tests a new treatment called AGAR T cells for children whose solid tumors (like liver cancer or rhabdomyosarcoma) have returned or not responded to standard care. The treatment involves taking a patient's own immune cells, adding genes to help them recogniz…

This study tests a virus-based drug (T-VEC) combined with radiation for adults with newly diagnosed soft tissue sarcoma that can be removed by surgery. The goal is to see if this combination can destroy most of the tumor before surgery and to check for side effects. About 40 peop…

This study tests whether adding the drug pazopanib to standard radiation or chemoradiation helps shrink soft tissue sarcomas before surgery. About 140 patients with newly diagnosed, removable tumors took part. The goal is to see if the combination is safe and improves tumor respo…

This early-stage study tests a drug called BTX-A51 in 24 people with advanced liposarcoma that has spread or come back. The main goal is to check if the drug is safe and tolerable at two different doses. Researchers will also watch for any tumor shrinkage or slowing of the diseas…

This study tests a new drug, PF-07220060, in people with advanced solid tumors (breast, prostate, lung, and others) that have not responded to standard treatments. The drug is given alone or with hormone therapies to see if it is safe and shrinks tumors. About 362 participants wi…