Lidocaine

This trial tests whether lidocaine or dexmedetomidine, given as infusions during functional endoscopic sinus surgery, can reduce bleeding and improve the surgeon's view. Forty adults aged 18 to 65 scheduled for elective sinus surgery will receive one of the two drugs after anesth…

This trial asks whether adding a steroid called dexamethasone to a local anesthetic (lidocaine) can improve pain relief after brain surgery (craniotomy). About 100 adults scheduled for this surgery will receive either the steroid-anesthetic mix or the standard anesthetic with epi…

This trial tests whether placing lidocaine and bupivacaine—two common local anesthetics—inside the abdomen and at incision sites during laparoscopic surgery can reduce pain right after the operation. Adults aged 18 to 60 scheduled for procedures like gallbladder removal or hernia…

This trial tests whether giving lidocaine, dexmedetomidine, or both during video-assisted thoracoscopic surgery (VATS) can reduce pain and the need for morphine afterward. Adults undergoing VATS under general anesthesia will receive one of the two drugs or a combination. The main…

This study tested whether using lidocaine instead of opioids during anesthesia induction can prevent low blood pressure in adults having emergency abdominal surgery. 149 patients were randomly assigned to receive either lidocaine-based or opioid-based anesthesia. The main goal wa…

This study tested two drugs, dexmedetomidine and lidocaine, given during surgery to control pain after a mastectomy. 40 women took part. The goal was to see which drug delays the need for extra pain medicine and keeps vital signs stable.

This study compares two drug combinations (ketamine-lidocaine vs ketamine-fentanyl) used to put patients to sleep before heart bypass surgery. The goal is to see which combination better maintains blood flow to the brain during the procedure. The study includes 40 adults with cor…