LANGERHANS CELL HISTIOCYTOSIS (LCH)
Clinical trials for LANGERHANS CELL HISTIOCYTOSIS (LCH) explained in plain language.
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New pill could spare kids with rare bone disease from chemo
Disease control Recruiting nowThis study tests a new oral drug, luvometinib, in children aged 0-18 with Langerhans cell histiocytosis (LCH) affecting special bones like the skull base or spine. The drug targets overactive cell signals that drive the disease. Researchers want to see if it can control the disea…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: NA • Sponsor: West China Second University Hospital • Aim: Disease control
Last updated May 26, 2026 08:33 UTC
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New combo therapy aims to beat tough childhood cancer
Disease control Recruiting nowThis study is for children aged 0-18 with a severe form of Langerhans cell histiocytosis (LCH) that affects multiple organs. It compares standard chemotherapy alone to the same chemotherapy plus a targeted drug called luvometinib. The goal is to see if adding luvometinib helps mo…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: NA • Sponsor: West China Second University Hospital • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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New drug shows promise for rare histiocytic diseases
Disease control Recruiting nowThis study tests a drug called mirdametinib in people with rare immune cell disorders like Langerhans cell histiocytosis. The goal is to see if it works better and has fewer side effects than current treatments. About 40 participants aged 2 and older will take the drug for up to …
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated May 20, 2026 11:55 UTC