KNEE OSTEOARTHRISTIS

This study tests a smart program for people with both knee osteoarthritis and obesity. The program uses AI-guided community exercise and continuous glucose monitoring to help control blood sugar, reduce knee pain, and improve daily function. Researchers will track 312 adults over…

This study compares two minimally invasive procedures for treating long-term knee pain caused by osteoarthritis. Fifty adults aged 45 to 85 with severe knee pain will be randomly assigned to receive either radiofrequency ablation (using heat) or a neurolytic alcohol injection to …

This study looks at whether a special knee and heel brace, combined with strength exercises that don't involve standing, can help people with knee osteoarthritis feel less pain and walk better. Twenty adults with knee arthritis will be split into two groups: one gets the new brac…

This study compares two blood flow restriction training methods—band tissue flossing and traditional cuff—to see which better reduces pain, improves movement, and strengthens muscles in people with knee osteoarthritis. 46 participants aged 40-60 with mild to moderate knee OA will…

This study looks at whether using an elastic band (tissue flossing) along with leg exercises helps people with knee osteoarthritis feel less pain and move better. About 58 adults aged 40-70 with mild to moderate knee arthritis will be split into two groups: one does exercises onl…

This study compares two exercise programs—sensory-motor training and resistance training—to see which better reduces pain, improves balance, and helps with daily activities in people with early-stage knee osteoarthritis. Researchers will enroll 52 adults aged 40-60 with mild knee…

This study tests whether adding a gentle nerve treatment (femoral nerve mobilization) to standard physical therapy can reduce pain and improve daily function in people with knee osteoarthritis. About 50 adults aged 50 and older with mild to moderate knee arthritis will be randoml…

This study compares focused shockwave therapy to standard physical rehabilitation for people with mild to moderate knee osteoarthritis (grades I-III). The goal is to see if shockwave therapy alone can reduce pain better than rehab. Sixty participants will be randomly assigned to …

This study looks at whether a single injection of hyaluronic acid can safely reduce pain and stiffness in adults with knee osteoarthritis. Normally, several shots are needed, but one dose could mean fewer clinic visits and lower costs. Researchers will review medical records from…

This study tests two types of leg exercises (close-chain and open-chain) done with a blood flow restriction band to see which better reduces pain and improves movement in people with mild knee osteoarthritis. Forty adults aged 45-75 with grade 1 or 2 knee OA will be split into tw…

This phase 3 study tests whether a single injection of MAG200 stem cells can reduce pain and improve daily function in adults with knee osteoarthritis. About 573 participants will receive either a low or high dose of stem cells or a placebo. The goal is to see if this treatment o…

This study tests whether combining blood-flow-restricted exercise (light exercise with a cuff on the leg) and pain education can reduce pain and improve function in adults with knee osteoarthritis. About 90 people aged 40 and older will take part. The goal is to see if this appro…

This study looks at two different FDA-approved machines that create platelet-rich plasma (PRP) for people with knee osteoarthritis. PRP is made from your own blood and may help with joint pain and stiffness. The researchers will check if the PRP from each machine has different am…