HYPOVOLEMIA

This study looks at 48 critically ill adults on breathing machines who may need fluids. Researchers will compare two methods—pulse pressure variation and a heart ultrasound technique—to see which better predicts if a patient will benefit from more fluids. The goal is to help doct…

This study will enroll 80 adults in the emergency department who are in shock (very low blood pressure). Researchers will compare two methods to detect low blood volume: an ultrasound of a large vein in the belly versus a standard pressure monitor placed near the heart. The goal …

This study looks at whether measuring changes in exhaled carbon dioxide during a leg-raising maneuver can help predict if a critically ill patient on a breathing machine needs more fluids. Researchers will observe 68 adults in the intensive care unit and compare this simple, non-…

This study is observing the safety and effectiveness of a plant-based human albumin in about 2,000 patients who urgently need treatment for low blood albumin or low blood volume. Doctors decide whether to use the drug based on standard care, and researchers track side effects and…