HYPEREOSINOPHILIC SYNDROME
Clinical trials for HYPEREOSINOPHILIC SYNDROME explained in plain language.
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New hope for rare blood disorder: Add-On drug shows promise
Disease control Recruiting nowThis study tests whether adding dupilumab to standard treatment can help adults with hypereosinophilic syndrome (HES) who still have symptoms. HES causes too many eosinophils, damaging organs. About 30 participants will receive dupilumab injections for up to 48 weeks. The goal is…
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated May 26, 2026 05:45 UTC
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New hope for rare blood disorder: drug aims to tame dangerous flares
Disease control Recruiting nowThis study tests an investigational drug called depemokimab in adults with hypereosinophilic syndrome (HES) that is not well controlled by current treatments. About 123 participants will receive either depemokimab or a placebo added to their usual therapy for 52 weeks. The main g…
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Phase: PHASE3 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New hope for rare blood disorder: ruxolitinib trial targets eosinophils
Disease control Recruiting nowThis study tests the drug ruxolitinib in 10 people with hypereosinophilic syndrome or related disorders, where high levels of eosinophils (a type of white blood cell) cause organ damage. The goal is to see if ruxolitinib can lower eosinophil counts and improve symptoms. Participa…
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Phase: PHASE2 • Sponsor: William Shomali • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC
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Scientists launch national effort to unravel mysteries of rare blood disorder
Knowledge-focused Recruiting nowThis study is creating a national group of 600 people with chronic high levels of eosinophils (a type of white blood cell) or related organ damage. Researchers want to understand the different symptoms, how the disease changes over time, and what genetic or environmental factors …
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 26, 2026 05:45 UTC
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Scientists track rare family disorder to unlock hidden clues
Knowledge-focused Recruiting nowThis study follows about 50 family members who have a genetic condition causing high levels of a certain white blood cell, which can damage organs. Researchers will track their health over many years with yearly check-ups and tests to learn how the disease progresses and find bet…
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC