Homozygous familial hypercholesterolemia
Clinical trials for Homozygous familial hypercholesterolemia explained in plain language.
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Can a single infusion fix a genetic cause of Sky-High cholesterol?
Cure Recruiting nowThis early trial tests a gene therapy called NGGT006 in people with homozygous familial hypercholesterolemia, a rare inherited condition causing extremely high LDL cholesterol and early heart disease. The therapy uses a harmless virus to deliver a working copy of the LDL receptor…
Matched conditions: HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
Early phase 1 • Sponsor: First Affiliated Hospital Xi'an Jiaotong University • Aim: Cure
Last updated Sep 05, 2026 00:00 UTC
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New repository aims to unlock secrets of rare, deadly cholesterol disease
Knowledge-focused Recruiting nowThis study creates a database of health information and blood samples from up to 60 children and adults with homozygous familial hypercholesterolemia (hoFH), a rare genetic condition causing extremely high cholesterol from birth. Researchers will track participants over time to l…
Matched conditions: HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
Sponsor: The Rogosin Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Worldwide effort to unlock secrets of rare cholesterol disease
Knowledge-focused Recruiting nowThis study is building a global database of 1000 people with homozygous familial hypercholesterolemia (HoFH), a rare inherited condition causing extremely high cholesterol from birth. Researchers are gathering de-identified medical data from clinics around the world to better und…
Matched conditions: HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC