High-grade B-cell lymphoma (HGBCL)
Clinical trials for High-grade B-cell lymphoma (HGBCL) explained in plain language.
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Engineered immune cells take on tough lymphomas
Disease control Recruiting nowThis phase 2 trial tests a personalized cell therapy called zamtocabtagene autoleucel (MB-CART2019.1) for people with B cell lymphomas that have come back or not responded to standard treatments. Participants receive their own immune cells that have been genetically modified to r…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA (HGBCL)
Phase 2 • Sponsor: Miltenyi Biomedicine GmbH • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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New 'Double Punch' CAR T-Cell therapy takes on tough blood cancers
Disease control Recruiting nowThis early-phase trial is testing a new cell therapy called GF-CART01 for people with certain B-cell blood cancers (like lymphoma) that have come back or not responded to standard treatments. The therapy uses a patient's own immune cells, modified to target two cancer markers (CD…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA (HGBCL)
Phase 1 • Sponsor: GenomeFrontier Therapeutics TW Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Engineered immune cells take on tough blood cancers in new trial
Disease control Recruiting nowThis study tests a personalized cell therapy called Talikabtagene Autoleucel for people with B-cell leukemia or lymphoma that has returned or not responded to standard treatment. The therapy uses a patient's own immune cells, which are modified in a lab to recognize and attack ca…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA (HGBCL)
Phase 2/3 • Sponsor: Health Institutes of Turkey • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Last-Resort drug made available for lymphoma patients
Disease control Expanded accessThis program provides compassionate use of odronextamab for people with relapsed or refractory follicular lymphoma, diffuse large B-cell lymphoma, or other B-cell non-Hodgkin lymphomas who have no other treatment options. Odronextamab is a drug that helps the immune system attack…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA (HGBCL)
Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC