HER2-POSITIVE BREAST CARCINOMA
Clinical trials for HER2-POSITIVE BREAST CARCINOMA explained in plain language.
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Targeted drug trial aims to starve advanced cancers by blocking their DNA repair
Disease control Recruiting nowThis study is testing whether the drug talazoparib can help control advanced cancers in patients whose tumors have specific genetic mutations that affect how cells repair damaged DNA. The trial will enroll about 36 adults with various advanced solid tumors (like breast, ovarian, …
Matched conditions: HER2-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 04, 2026 06:20 UTC
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Could some breast cancer patients safely skip surgery or radiation?
Disease control Recruiting nowThis study is testing whether some breast cancer patients who respond exceptionally well to initial drug therapy can safely avoid surgery or radiation. It aims to see if careful monitoring with biopsies and scans can be enough for these patients, potentially reducing the side eff…
Matched conditions: HER2-POSITIVE BREAST CARCINOMA
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Scientists test 'One-Two Punch' against Tough-to-Treat cancers
Disease control Recruiting nowThis early-stage study is testing the safety and best dose of a new two-drug combination for people with advanced solid tumors that have a specific marker called HER2. The treatment pairs an existing targeted cancer drug with a new pill that aims to block cancer cells' ability to…
Matched conditions: HER2-POSITIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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AI scans aim to predict breast cancer cure before surgery
Diagnosis Recruiting nowThis study is testing whether a special type of scan (PET/MRI), analyzed by artificial intelligence, can accurately tell if a patient's HER2-positive breast cancer has been completely eliminated by drug treatment before surgery. It aims to see if these scans can predict and confi…
Matched conditions: HER2-POSITIVE BREAST CARCINOMA
Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Diagnosis
Last updated Mar 31, 2026 12:11 UTC
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Cancer drugs under scrutiny for potential diabetes link
Knowledge-focused Recruiting nowThis study aims to understand if common hormone therapies for breast cancer affect how the body controls blood sugar and might increase diabetes risk. Researchers will compare 66 postmenopausal women—some taking specific cancer drugs, others not—by checking their blood sugar leve…
Matched conditions: HER2-POSITIVE BREAST CARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists track Body's hidden battle against breast cancer during treatment
Knowledge-focused Recruiting nowThis study aims to understand how the immune system reacts during standard treatments for HER2-positive breast cancer. Researchers will collect blood and tissue samples from 230 patients with stage I-IV breast cancer who are receiving or have received anti-HER2 drugs like trastuz…
Matched conditions: HER2-POSITIVE BREAST CARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC