HER2-NEGATIVE BREAST CARCINOMA

This large study is testing whether adding an immunotherapy drug called durvalumab to standard chemotherapy is better at preventing cancer from returning than chemotherapy alone. It is for adults with a specific high-risk type of breast cancer (HR-positive, HER2-negative, stage I…

This early-stage study aims to find the safest and most effective dose of the drug abemaciclib when given alongside radiation therapy to treat bone metastases in people with advanced, hormone-sensitive breast cancer. The study will enroll 28 adults whose cancer has spread and who…

This study is testing whether giving hormone therapy before surgery helps women with a specific type of breast cancer have better surgical outcomes. Researchers want to see if this approach reduces the chance that cancer cells are left at the edges of removed tissue, which often …

This large international study is testing whether a new drug called palazestrant works better than the current standard treatment when combined with another cancer drug called ribociclib. The trial will involve about 1,000 adults with advanced breast cancer that hasn't been treat…

This study is testing whether a smart pillbox, combined with text message reminders, can help people with advanced breast cancer remember to take their oral medication correctly. The goal is to see if this technology helps patients stick to their complex treatment schedule better…

This trial is testing whether a new oral medication called OP-1250 works better than current standard hormone therapies for people with advanced breast cancer that has continued to grow despite previous hormone treatments. The study will enroll about 510 adults whose cancer is ho…

This early-stage trial is testing a new treatment for people with metastatic pancreatic or breast cancer. The goal is to see if a combination of high-dose chemotherapy drugs, vitamins, and the patient's own stem cells is safe and can overcome the cancer's resistance to treatment.…

This study is testing whether taking turkey tail mushroom extract can slow the growth of breast cancer tumors in the weeks between diagnosis and surgery. It involves 40 post-menopausal women with a common hormone-driven type of breast cancer who are not yet on other cancer drugs.…

This study is testing whether a lower dose of a common chemotherapy combination (docetaxel and cyclophosphamide) works as well as the standard dose for women aged 65 and older with early-stage breast cancer. The main goal is to see if the reduced dose is easier to tolerate, cause…

This study is testing whether a 10-week stress reduction program is practical and helpful for patients with triple-negative breast cancer. The program teaches relaxation, coping skills, and problem-solving, and also connects patients with social services for needs like transporta…

This study is testing whether acupuncture or virtual acupressure can prevent severe joint pain caused by a common breast cancer medication. It focuses on Non-Hispanic Black postmenopausal women with early-stage breast cancer, as they are more likely to experience this side effect…

This study aims to collect real-world information about how well FDA-approved antibody-drug conjugate (ADC) treatments work for people with advanced HER2-negative breast cancer. Researchers will follow 100 patients receiving these treatments as part of their regular care to under…