HER-2 POSITIVE BREAST CANCER
Clinical trials for HER-2 POSITIVE BREAST CANCER explained in plain language.
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New drug combo aims to shrink breast tumors before surgery
Disease control OngoingThis study tests whether giving two targeted drugs, T-DM1 and pertuzumab, before surgery can eliminate or shrink HER2-positive breast tumors in people with stage II or III cancer. The 164 participants receive the drugs for 18 weeks, then undergo surgery. The main goal is to see h…
Matched conditions: HER-2 POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 23, 2026 23:48 UTC
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New combo aims to outsmart resistant breast cancer
Disease control OngoingThis phase 2 trial tests whether combining sacituzumab govitecan (Trodelvy) with trastuzumab (Herceptin) can shrink tumors in people with HER2+ metastatic breast cancer who have already been treated with trastuzumab deruxtecan. The study enrolls 28 participants and measures how m…
Matched conditions: HER-2 POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Adrienne G. Waks • Aim: Disease control
Last updated Jun 23, 2026 11:56 UTC
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New drug cocktail shows promise for Tough-to-Treat breast cancer
Disease control OngoingThis study tests whether adding the drug palbociclib to standard hormone and anti-HER2 therapy helps people with a specific type of advanced breast cancer (HR+/HER2+) live longer without the disease getting worse. About 518 adults with metastatic breast cancer that cannot be remo…
Matched conditions: HER-2 POSITIVE BREAST CANCER
Phase: PHASE3 • Sponsor: Alliance Foundation Trials, LLC. • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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Can we predict Chemo's heart harm? new study aims to find out
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 700 breast cancer patients to understand how chemotherapy affects the heart. Researchers use echocardiograms and blood tests to find early signs of heart damage. The goal is to better predict and prevent cardiotoxicity in cancer treatment.
Matched conditions: HER-2 POSITIVE BREAST CANCER
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:00 UTC