HEPATOBLASTOMA
Clinical trials for HEPATOBLASTOMA explained in plain language.
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Engineered immune cells take on childhood cancers in first human test
Disease control OngoingThis early-stage trial tests a new type of immunotherapy for children and young adults with solid tumors that have not responded to standard treatments. The therapy uses the patient's own immune cells (T cells) that are genetically modified to recognize and attack cancer cells ca…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 23, 2026 22:01 UTC
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New flavored chemo drink aims to ease treatment for kids with hard-to-treat cancers
Disease control OngoingThis early-phase study tests a flavored, drinkable version of the chemotherapy drug irinotecan (VAL-413) combined with another drug (temozolomide) in children and young adults up to age 30 whose solid tumors have come back. The main goal is to find the safest dose and see how the…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Valent Technologies, LLC • Aim: Disease control
Last updated Jun 22, 2026 12:06 UTC
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New hope for kids with rare cancers: targeted drug shows promise
Disease control OngoingThis study tests a daily pill called cabozantinib in children and young adults (up to age 30) with rare cancers like sarcomas, Wilms tumor, and others that have come back or not responded to treatment. The drug works by blocking signals that help tumors grow and form blood vessel…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 22, 2026 12:05 UTC
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New drug combo hopes to fight tough cancers in kids and young adults
Disease control OngoingThis study tests a combination of two drugs, cobolimab and dostarlimab, in children and young adults (up to age 21) with advanced solid tumors that have not responded to other treatments. The goal is to find the safest dose and see if the combination can shrink tumors. The study …
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 18, 2026 11:49 UTC
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Engineered immune cells take aim at childhood cancers in early trial
Disease control OngoingThis early-phase study tests a personalized cell therapy for children and young adults (up to age 26) with solid tumors that have come back or not responded to standard treatment. The therapy uses the patient's own immune cells, modified to recognize and attack a protein called B…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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New hope for kids with rare liver tumors: tailored therapy trial shows promise
Disease control OngoingThis study tests different treatment plans based on each child's risk level for two rare liver cancers: hepatoblastoma and hepatocellular carcinoma. About 450 children will receive chemotherapy and possibly surgery, with the goal of preventing the cancer from coming back. The app…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE3 • Sponsor: University of Birmingham • Aim: Disease control
Last updated Jun 10, 2026 13:26 UTC
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New hope for kids with liver cancer: international trial tests smarter chemo combos
Disease control OngoingThis study tests different combinations of chemotherapy drugs, along with surgery, for children and young adults with two types of liver cancer: hepatoblastoma and hepatocellular carcinoma. The goal is to see which combinations work best to stop tumor growth and improve survival.…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 08, 2026 13:08 UTC