HEPATIC INSUFFICIENCY

This study looked at how the drug BI 1015550 is processed in people with mild or moderate liver problems compared to those with healthy livers. Twenty-eight adults took a single dose of the drug, and researchers measured its levels in the blood over time. The goal was to understa…

This study tested how the drug olomorasib enters the blood and how long it takes the body to remove it in people with mild, moderate, or severe liver problems compared to healthy people. 46 adults took a single dose and were monitored for up to 6 weeks. The goal was to understand…

This study looked at whether a special liver scan (hepatobiliary scintigraphy) can predict the risk of liver failure after major liver surgery. 326 adults without cirrhosis who needed large liver resections were included. The goal was to see if the scan's measurement of liver fun…

This study looked at how imlunestrant enters the blood and leaves the body in women with liver problems compared to healthy women. 27 women took part, and the goal was to understand the drug's behavior, not to treat any condition. Results help guide future dosing for patients wit…

This study looked at how the drug bomedemstat (MK-3543) moves through the body in people with mild or moderate liver problems compared to healthy volunteers. Nine participants received a single dose, and researchers measured drug levels in the blood. The goal was to understand if…

This study looked at how moderate liver problems affect the way the body handles a new cancer medicine called sevabertinib. About 20 people (10 with liver impairment and 10 healthy) took a single dose and had their blood levels measured. The goal is to help doctors decide the rig…

This study looked at how the experimental brain medicine iclepertin is processed in people with and without liver problems. About 29 adults took a single dose of the drug, and researchers measured its levels in the blood. The goal was to see if liver impairment changes how the bo…