Tiny study tests how liver disease changes drug processing

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria The main inclusion criteria include but are not limited to the following: * Is a non-smoker or is a moderate smoker for at least 3 months prior to dosing Participants with Mild and Moderate HI * Is classified as having either mild HI (Group 1) or moderate HI (Group 2) score on the Child-Pugh scale ranging from 5 to 6 (mild) or 7 to 9 (moderate) * Has a diagnosis of chronic (\> 6 months), stable (no acute episodes of illness within the previous 2 months due to deterioration in hepatic function) hepatic insufficiency with features of cirrhosis due to any etiology Healthy Control Participants: * Must match the mean age (± 15 years) of participants with mild HI and moderate HI * Must match the mean body-mass index (BMI) (± 25%) of participants with mild HI (Group 1) and moderate HI * Must match the sex ratio (±2) of participants in each HI group, separately Exclusion Criteria The main exclusion criteria include but are not limited to the following: All Participants * History of cancer (malignancy) * Female participants of childbearing potential * Is positive for Hepatitis C virus (HCV) * Is positive for Hepatitis B surface antigen (HBsAg) * Is positive for human immunodeficiency virus (HIV) Participants with Mild and Moderate HI * Has any significant arrhythmia or conduction abnormality * Severe complications of liver disease within the preceding 3 months * Primary biliary cholangitis or biliary obstruction * Has a history of a recent variceal bleeds * Has evidence of hepatorenal syndrome * Has a history of liver or other solid organ transplantation * Has an active infection requiring systemic therapy * Requires paracentesis more often than 2 times per month * Has transjugular intrahepatic portosystemic shunt and/or has undergone portacaval shunting Healthy Control Participants * Has a history of clinically significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases * Is a regular user of cannabis products within approximately 6 months of study