HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Clinical trials for HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS explained in plain language.
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Milder stem cell transplant offers hope for kids with rare immune diseases
Disease control OngoingThis study tests a less intense stem cell transplant for children and young adults up to age 28 with various immune system disorders. The goal is to see if a milder pre-transplant treatment can help donor cells take hold with fewer serious side effects. The study tracks engraftme…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 26, 2026 08:02 UTC
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Promising new combo therapy targets rare immune disease in kids
Disease control OngoingThis study tests a combination of three drugs (ruxolitinib, dexamethasone, and etoposide) for children and young adults with a severe immune condition called HLH. The goal is to see if this treatment can control the disease better and with fewer side effects. Participants receive…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: PHASE1, PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 26, 2026 07:54 UTC
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Stem cell transplant offers new hope for kids with rare immune diseases
Disease control OngoingThis study tests a donor stem cell transplant to treat severe immune system problems in 57 people. The goal is to help the body make healthy blood cells and fight infections. Patients must have a specific immune disorder and meet health criteria to join.
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated May 26, 2026 07:25 UTC