HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Clinical trials for HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS explained in plain language.
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New hope for kids with rare, Life-Threatening immune storm
Disease control OngoingThis study is testing a new treatment approach for hemophagocytic lymphohistiocytosis (HLH), a rare and severe immune system disorder. It combines three drugs—ruxolitinib, dexamethasone, and etoposide—in a flexible plan that adjusts based on how each patient responds. The goal is…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: PHASE1, PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Gentler transplant offers hope for kids with 'Bubble Boy' and other immune diseases
Disease control OngoingThis study is testing a less intense stem cell transplant procedure for children and young adults with rare immune system disorders. The goal is to see if using lower doses of chemotherapy and radiation before the transplant can help the donor cells take hold while reducing sever…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New hope: rebuilding broken immune systems with donor cells
Disease control OngoingThis study is testing a treatment to rebuild the immune system in people with severe inherited immune deficiencies. Patients receive stem cells from a donor, which are meant to grow into healthy new immune cells. The goal is to control the disease and reduce life-threatening infe…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC