HEMATOPOIETIC CELL TRANSPLANT

This study looks at whether stopping the anti-CMV drug letermovir based on a patient's immune system response can prevent CMV infections better than taking it every day. It involves 105 stem cell transplant recipients who are at high risk for CMV reactivation. Researchers will mo…

This study tests whether giving the immune-suppressing drug tacrolimus earlier than usual can lower the risk of cytokine release syndrome (a severe immune reaction) in people receiving a half-matched stem cell transplant for blood cancer. About 20 adults will take part, and resea…

This study tests a new program called Sentinel that helps doctors provide extra comfort and support to patients getting a stem cell transplant. The program focuses on improving quality of life and managing symptoms during treatment. About 40 adults will take part to see if the pr…

This study tests whether a 12-week virtual physical therapy program is practical and helpful for children and young adults (ages 8-23) who are at least 100 days past a bone marrow transplant. Participants will have twice-weekly online sessions with a physical therapist and receiv…

This study looks at whether a computer brain-training program called Lumosity can help improve memory and thinking in people who have had a stem cell transplant for blood cancer. About 60 adults who are 3 to 6 months post-transplant will either start training right away or wait 1…

This study looks at children who have had or will have a stem cell or organ transplant. Researchers want to see if testing for viruses before the transplant can help predict if the child will get a serious respiratory infection in the next year. They will also study the child's i…