HEMATOLOGICAL MALIGNANCIES
Clinical trials for HEMATOLOGICAL MALIGNANCIES explained in plain language.
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New drug after transplant shows promise for blood cancer patients
Disease control CompletedThis study looked at whether giving a drug called cyclophosphamide after a stem cell transplant could help the new cells settle in better and reduce serious side effects like graft-versus-host disease (GVHD). It involved 78 people with blood cancers who received stem cells from a…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated May 26, 2026 09:39 UTC
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New Two-Step transplant shows promise against tough blood cancers
Disease control CompletedThis study tested a two-step stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. The approach uses a drug called cyclophosphamide to lower the chance of graft-versus-host disease (GVHD), a serious side effect. The goal was to help more patient…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated May 26, 2026 09:30 UTC
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New combo therapy shows promise for tough blood cancers
Disease control CompletedThis study tested a new drug combination (MK-7684A) in 192 adults with blood cancers like lymphoma and multiple myeloma that had returned or stopped responding to other treatments. The main goals were to see if the drug is safe and to measure how well it shrinks tumors. The appro…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 26, 2026 08:19 UTC
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Supercharged cord blood transplant shows promise for faster recovery in blood cancer patients
Disease control CompletedThis study tested a special stem cell product called NiCord, made by growing cord blood cells in a lab to increase their number. It was compared to standard cord blood transplants in 125 people with blood cancers like leukemia and lymphoma. The goal was to see if NiCord could hel…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE3 • Sponsor: Gamida Cell ltd • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Gene type may affect how cancer drug works in patients
Knowledge-focused CompletedThis early-phase study looked at how the cancer drug belinostat is processed in the body depending on a person's UGT1A1 gene type. It included 17 adults with advanced solid tumors or blood cancers that had stopped responding to standard treatments. Researchers measured drug level…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE1 • Sponsor: Acrotech Biopharma Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 09:39 UTC
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PET scans tested to guide therapy for hidden fungal infection
Knowledge-focused CompletedThis study looked at whether a special scan (PET scan) can help doctors decide the best treatment for a rare fungal infection of the liver and spleen in people with blood cancer. One hundred adults who had recently recovered from low white blood cell counts and had suspicious spo…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 11, 2026 20:50 UTC