HEALTHY VOLUNTEER STUDY

This early-stage study is testing a single dose of the drug combination bemnifosbuvir/ruzasvir in 28 adults. Some participants have severe kidney or liver impairment, while others are healthy. The goal is to see how the body processes the drug and whether it is safe in these grou…

This study will intentionally expose 72 healthy adults to the bacteria that cause whooping cough to see how the body fights it off without immediate antibiotics. Participants will be monitored closely for up to 6 weeks before receiving antibiotics to clear the infection. The goal…

This study tests whether a small vibrating device placed on the thigh can prevent muscle loss and weakness in healthy adults during a period of reduced activity. 42 participants will have one leg immobilized and either receive focal muscle vibration or no treatment. The goal is t…

This early-phase study looks at how heat stress changes kidney function in 28 healthy, fit volunteers. Researchers want to understand the body's chemical responses and whether taking vitamin B3 (niacinamide) can influence those changes. The goal is to gather knowledge, not to tre…

This study looks at how a new experimental drug combination (BEM/RZR) changes the levels of common opiate withdrawal medications (buprenorphine/naloxone or methadone) in the blood. It involves 32 healthy volunteers who are already on stable therapy for opiate withdrawal. The goal…

This study looks at how a protein called NaV1.8, found in pain-sensing nerves, contributes to different kinds of pain. Healthy volunteers receive tiny, safe doses of a drug that blocks NaV1.8 directly into their skin, then undergo brief pain tests (like heat, cold, or pressure). …

This study looks at how gentle touch on different parts of the ear changes brain activity in healthy adults. Researchers will use a special cap with infrared light sensors to measure brain responses while stimulating the ear with soft plastic filaments. The goal is to understand …