HEALTHY SUBJECTS (HS)

This study tests whether adding a small amount of hydrogen to the breathing gas can reduce lung damage caused by breathing high levels of oxygen under pressure. Thirty-two healthy military divers will each complete two sessions—one with hydrogen and one without—to compare effects…

This study will use advanced PET scans to measure blood flow and energy use in the brain and body at the same time. Researchers want to see how these responses differ between healthy adults and people with heart disease, especially during mental or physical stress. The goal is to…

This early-phase study tests the safety and tolerability of a new oral drug called ISM8969 in healthy adults, elderly adults, and obese adults at risk for heart disease. About 100 participants will receive either the drug or a placebo to check for side effects and how the drug mo…

This study aims to create a standard method for collecting and analyzing skin oil (sebum) to find biomarkers for skin diseases like acne, eczema, and psoriasis. Researchers will study 200 participants, including healthy people and those with skin conditions, to see how skin oil c…

This early-stage study tests a new drug called ISH0613 in 26 healthy adults to see if it is safe and how the body handles it. Participants get a single dose of the drug or a placebo and are closely monitored for side effects. The results will help guide future research in conditi…