HEADACHE DISORDERS
Clinical trials for HEADACHE DISORDERS explained in plain language.
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Online therapy plus pill may cut Kids' migraines in half
Prevention Recruiting nowThis study tests whether adding a daily pill (amitriptyline) to online cognitive behavioral therapy (CBT) helps prevent migraines in children better than online therapy alone. About 400 kids with frequent migraines will be followed for months to see if headache days drop by half …
Matched conditions: HEADACHE DISORDERS
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Prevention
Last updated Jun 15, 2026 19:09 UTC
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Teens with migraine get a new Non-Drug option: group therapy with exercise and relaxation
Symptom relief Recruiting nowThis study tests a group therapy program for teens aged 13-17 with migraine. The program combines high-intensity interval training, progressive muscle relaxation, and education over 18 weeks. Researchers want to see if it reduces headache frequency, pain, and the need for medicat…
Matched conditions: HEADACHE DISORDERS
Phase: NA • Sponsor: Medical University Innsbruck • Aim: Symptom relief
Last updated Jun 22, 2026 12:09 UTC
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Scalp block may cut opioid use for brain bleed headaches
Symptom relief Recruiting nowThis study tests whether a scalp block (a numbing injection) can reduce severe headaches in patients who have had a brain aneurysm rupture. About 22 adults in intensive care will receive either standard care plus the scalp block or standard care alone. The goal is to see if the b…
Matched conditions: HEADACHE DISORDERS
Phase: NA • Sponsor: Hamad Medical Corporation • Aim: Symptom relief
Last updated Jun 22, 2026 12:05 UTC
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No-Pill migraine fix? mayo clinic tests lifestyle training to cut headaches
Symptom relief Recruiting nowThis pilot study from Mayo Clinic tests whether a virtual lifestyle behavior training program can help people with chronic migraine have fewer attacks. Sixty adults with chronic migraine for at least one year will be randomly assigned to either the lifestyle program or a sham edu…
Matched conditions: HEADACHE DISORDERS
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 22, 2026 11:58 UTC
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Exercise may ease migraine pain and disability, new study suggests
Symptom relief Recruiting nowThis study looks at whether a 16-week supervised aerobic exercise program, combined with a session on pain education, can reduce migraine-related disability and improve quality of life in women aged 18 to 48. One hundred participants will be randomly assigned to either the exerci…
Matched conditions: HEADACHE DISORDERS
Phase: NA • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Jun 17, 2026 12:04 UTC
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Can a Mind-Body program cut Kids' migraines? new study seeks answers
Symptom relief Recruiting nowThis study is testing a nurse-led mind-body program to help children and teens with migraine have fewer headache days. The program combines different treatment parts, like relaxation and coping skills, to find the best mix. The study will include 260 participants aged 10-17 who h…
Matched conditions: HEADACHE DISORDERS
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Symptom relief
Last updated Jun 15, 2026 19:04 UTC
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Migraine study unlocks secrets of placebo vs. real drug effects
Knowledge-focused Recruiting nowThis study aims to understand how the information given to patients about their treatment affects their response to migraine medication. Researchers will give 60 adults with chronic migraine four different treatment conditions in a random order and measure changes in headache int…
Matched conditions: HEADACHE DISORDERS
Phase: NA • Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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Headache study digs into brain and personality to improve treatment
Knowledge-focused Recruiting nowThis study looks at how thinking skills, personality, and pain sensitivity affect headache treatment in 64 adults with chronic or episodic headaches. Researchers will track participants for about six months to understand what helps or hinders treatment success. The goal is to fin…
Matched conditions: HEADACHE DISORDERS
Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:08 UTC