H3 K27M
Clinical trials for H3 K27M explained in plain language.
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Hope for rare brain tumor: phase 3 trial of ONC201 launches
Disease control Recruiting nowThis Phase 3 trial tests the drug ONC201 (dordaviprone) in people newly diagnosed with a rare brain cancer called H3 K27M-mutant diffuse glioma. Participants receive either ONC201 or a placebo after completing standard radiotherapy. The study aims to see if the drug helps them li…
Matched conditions: H3 K27M
Phase: PHASE3 • Sponsor: Jazz Pharmaceuticals • Aim: Disease control
Last updated Jun 23, 2026 11:56 UTC
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Direct brain infusion trial offers new hope for kids with relapsed glioma
Disease control Recruiting nowThis study tests whether giving two drugs (cetuximab and bevacizumab) directly into the brain's blood vessels each month is safe and can shrink tumors or slow their growth. It includes children and young adults under 22 with certain types of brain tumors that have come back or no…
Matched conditions: H3 K27M
Phase: PHASE1, PHASE2 • Sponsor: University of Miami • Aim: Disease control
Last updated Jun 22, 2026 12:06 UTC