H3 K27M
Clinical trials for H3 K27M explained in plain language.
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New hope for kids with brain cancer: targeted drug infusions show promise
Disease control Recruiting nowThis study tests the safety and effectiveness of giving two cancer drugs (cetuximab and bevacizumab) directly into the brain's arteries each month for children and young adults under 22 with brain tumors that have come back or not responded to treatment. About 20 participants wil…
Matched conditions: H3 K27M
Phase: PHASE1, PHASE2 • Sponsor: University of Miami • Aim: Disease control
Last updated Jun 17, 2026 01:28 UTC
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Promising pill takes on deadly childhood brain tumor in global trial
Disease control Recruiting nowThis study tests a drug called ONC201 (dordaviprone) in people newly diagnosed with a rare and aggressive brain tumor (H3 K27M-mutant glioma). After completing standard radiation, participants receive either ONC201 or a placebo to see if the drug helps them live longer and delays…
Matched conditions: H3 K27M
Phase: PHASE3 • Sponsor: Jazz Pharmaceuticals • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC