GYNECOLOGIC CANCERS

This study tests an experimental drug called IMGN151 for people with gynecologic cancers, including ovarian cancer. The drug is given alone or with other cancer treatments to see if it is safe and works. About 377 adults will take part at sites worldwide. The goal is to find bett…

This study compares two types of stitches used to close the top of the vagina after a hysterectomy (removal of the uterus) for gynecologic cancers. The goal is to see if a newer double-layer self-locking stitch reduces complications like infection, bleeding, or reopening of the i…

This study tests whether adding a vitamin A-like drug (ATRA) to a platelet-boosting medication (romiplostim N01) works better than the platelet drug alone for cancer survivors whose platelet counts stay low after chemotherapy. About 220 adults with gynecologic, breast, or lung ca…

This study tests an FDA-approved dye called CYTALUX (pafolacianine) that attaches to cancer cells and glows under a special camera during surgery. About 50 adults with certain gastrointestinal or gynecologic cancers will get the dye before their operation. The goal is to see if t…

This study is testing a virtual program called Mindful After Cancer (MAC) to help breast and gynecologic cancer survivors with sexual health and body image concerns. About 60 participants will be randomly assigned to either the 8-week MAC program or receive educational materials …

This study tests a one-time, 30-minute financial education session for people with gynecologic cancer and their caregivers. The goal is to see if the program is practical and helps patients feel more confident and less stressed about the costs of cancer care. About 36 participant…

This study looks at 140 women having surgery for gynecologic cancer. Half will get standard wound closure (staples or stitches), and half will get cosmetic stitches under the skin. The goal is to see if the cosmetic method improves body image, satisfaction with the scar, and mood…

This study is testing an online program called eSense-Cancer to help people who have had gynecologic cancer with sexual health concerns. About 60 participants will use the program and report changes in sexual distress and satisfaction. The goal is to see if this online tool can p…

This study tests whether an educational video and workbook can help gynecologic cancer patients bring up sexual health concerns with their doctors. About 200 patients will either receive the program plus a resource booklet, or just the booklet with usual care. Researchers will co…

This study compares three standard pain management methods used during minimally invasive cancer surgery. 48 adults having surgery for cancers of the liver, stomach, pancreas, or other organs will be randomly assigned to one of three groups. The goal is to see which method provid…

This study tests an 8-week program called HEAL-GYN for people who have finished chemotherapy for gynecologic cancer. The program focuses on healthy eating and physical activity to improve confidence, mental health, and overall well-being. Researchers will measure changes in eatin…

This study follows 200 women with gynecologic cancer and their partners over a year to see how sexual function changes. Participants fill out questionnaires at diagnosis, 6 months, and 12 months after treatment. The goal is to understand when sexual counseling might be most helpf…

This study collects blood and tumor samples from up to 3,300 people with a high genetic risk for breast, ovarian, or related cancers. Researchers aim to understand how these cancers develop and how treatments work. Participants include those with BRCA1/2 or other gene mutations, …

This study looks at whether hospitals in India are following standard guidelines for treating cervical cancer with radiation and chemotherapy. Researchers will review records from over 600 patients across many hospitals to see how often the recommended treatment is given correctl…