GRAVES OPHTHALMOPATHY

This study tests whether statin therapy and vitamin D supplements can help control active thyroid eye disease, a condition that causes eye bulging and discomfort. About 120 adults with active disease will be randomly assigned to one of four groups: standard care alone, statin plu…

This study tests an oral medication called tofacitinib for people with moderate-to-severe thyroid eye disease who did not get better with or could not tolerate steroids. The drug works by blocking inflammation pathways. Eight participants will take tofacitinib twice daily for 24 …

This study examines how inflammation and thyroid antibodies relate to changes in the retina and optic nerve in people with Graves disease. Researchers will review medical records of 100 adults, comparing those with Graves disease (with or without eye involvement) to healthy contr…

This study aims to understand why some people with Graves' disease continue to experience mental fatigue even after their thyroid levels return to normal. Researchers will compare blood and spinal fluid samples from 180 participants—60 with mental fatigue, 60 without, and 60 heal…