GLIOBLASTOMA MULTIFORME (GBM)
Clinical trials for GLIOBLASTOMA MULTIFORME (GBM) explained in plain language.
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New hope for brain cancer patients as drug combo trial begins
Disease control Recruiting nowThis study tests a new drug called paxalisib combined with standard chemotherapy (temozolomide) in people with aggressive brain tumours like glioblastoma. The goal is to see if the combination is safe and can slow tumour growth or improve survival. About 64 participants will take…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE1, PHASE2 • Sponsor: Institute of Cancer Research, United Kingdom • Aim: Disease control
Last updated May 26, 2026 03:16 UTC
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New drug KESONOTIDE™ enters human trials for multiple cancers
Disease control Recruiting nowThis study tests a new experimental drug, KESONOTIDE™, in people with advanced solid tumors like prostate, breast, lung, ovarian, pancreatic, skin cancer, or glioblastoma. The main goal is to check the drug's safety and find the right dose. About 80 adults will take part in two p…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE1, PHASE2 • Sponsor: Filamon LTD • Aim: Disease control
Last updated May 26, 2026 03:13 UTC
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New hope for brain cancer: drug combo targets tough tumours
Disease control Recruiting nowThis trial tests two drugs, avutometinib and defactinib, alone or with a third drug (temozolomide), in people with aggressive brain tumours like glioblastoma. The goal is to see if the combination is safe and can shrink tumours or slow their growth. About 182 adults with recurren…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE1, PHASE2 • Sponsor: Institute of Cancer Research, United Kingdom • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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Immune cells injected into brain to fight tumors
Disease control Recruiting nowThis study tests a new treatment using natural killer (NK) cells, a type of immune cell, to fight malignant brain tumors in adults who have not responded to standard therapies. The NK cells are given both into the brain and through a vein to see if they are safe and can shrink tu…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: NA • Sponsor: Peking University Third Hospital • Aim: Disease control
Last updated May 26, 2026 02:48 UTC
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New hope for aggressive brain cancer? drug combo trial launches
Disease control Recruiting nowThis study tests whether adding an experimental drug called silevertinib to standard chemotherapy (temozolomide) helps people with a specific type of newly diagnosed glioblastoma live longer without their cancer growing. The trial is for patients whose tumors have certain genetic…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE2 • Sponsor: Black Diamond Therapeutics, Inc. • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Sound wave helmet could boost brain cancer treatment
Disease control Recruiting nowThis early-stage trial tests a special helmet that uses focused ultrasound to temporarily open the blood-brain barrier in people with glioblastoma, a severe brain cancer. The goal is to see if this approach is safe and can help standard chemotherapy reach the tumor more effective…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE1 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated May 22, 2026 13:55 UTC