Functional constipation (FC)

This trial tests whether fluoxetine, a common antidepressant, can improve bowel function in adults with chronic constipation that has not responded to standard laxatives. Participants also show features of somatic symptom disorder, where emotional distress appears as physical sym…

This trial tests whether a new non-invasive device, called Body Surface Colonic Mapping, can accurately measure colon movement in children. The device uses a sticky pad with electrodes placed on the abdomen to detect electrical activity from the colon. Researchers will compare it…

This trial tests whether adding physical therapy—including spinal joint mobilization, electrical muscle stimulation, and gentle abdominal techniques—to standard medical care can reduce constipation severity and improve quality of life in adults with functional constipation. Sixty…

This study tests whether a daily fiber supplement (Materna® Opti-fiber) plus nutrition counseling can help pregnant women with constipation. About 31 women between 13 and 27 weeks of pregnancy will take the supplement for 4 weeks. Researchers will track changes in stool frequency…

This study tests whether a combined exercise and abdominal massage program can improve bowel function and daily well-being in children aged 5-18 with functional constipation. Researchers will compare the program to standard care by measuring symptoms, rectal size, and quality of …