FTD-GRN
Clinical trials for FTD-GRN explained in plain language.
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New gene therapy targets inherited dementia in early trial
Disease control OngoingThis study tests a single dose of a gene therapy called PBFT02 in 30 adults with frontotemporal dementia caused by specific gene mutations. The treatment aims to deliver a working copy of the GRN gene to the brain to help control the disease. Researchers are primarily checking sa…
Matched conditions: FTD-GRN
Phase: PHASE1, PHASE2 • Sponsor: Passage Bio, Inc. • Aim: Disease control
Last updated May 20, 2026 11:58 UTC
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Simple blood draws from home could predict dementia years before symptoms
Knowledge-focused OngoingThis study collects blood samples every 3 months for 3 years from people who carry gene mutations linked to frontotemporal dementia (FTD), a brain disease that affects personality and language. The goal is to see if a protein called neurofilament light chain (NfL) changes over ti…
Matched conditions: FTD-GRN
Sponsor: The Bluefield Project to Cure Frontotemporal Dementia • Aim: Knowledge-focused
Last updated May 26, 2026 05:27 UTC