FRACTURES, OPEN
Clinical trials for FRACTURES, OPEN explained in plain language.
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Could a simple injection slash infection risk in open fractures?
Prevention OngoingThis study tests whether adding a local antibiotic (tobramycin) directly into the wound, along with standard IV antibiotics, can lower infection rates after open fracture surgery. Open fractures have a high risk of infection because blood flow to the injured area is often poor. T…
Matched conditions: FRACTURES, OPEN
Phase: PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Prevention
Last updated May 26, 2026 07:50 UTC
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Shorter antibiotic course may be just as safe for kids with open fractures
Prevention ENROLLING_BY_INVITATIONThis study looks at 800 children with mild open fractures to see if a single dose of antibiotics works as well as longer treatments to prevent infections. Participants will receive either one dose, 24 hours, or 24 hours plus 5 days of oral antibiotics. The goal is to find the saf…
Matched conditions: FRACTURES, OPEN
Phase: PHASE4 • Sponsor: St. Louis University • Aim: Prevention
Last updated May 26, 2026 07:23 UTC