First episode psychosis (FEP)
Clinical trials for First episode psychosis (FEP) explained in plain language.
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New therapy aims to help psychosis patients quit cannabis
Disease control Not yet recruitingThis study tests a talking therapy called the Cannabis Clinic for Psychosis (CCP) to help people with first-episode psychosis reduce or stop cannabis use. The therapy includes motivational interviewing and cognitive behavioral therapy in weekly sessions over 12 weeks. Researchers…
Matched conditions: FIRST EPISODE PSYCHOSIS (FEP)
Sponsor: King's College London • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Pumping iron to slow aging: exercise trial targets psychosis patients
Disease control Not yet recruitingThis study looks at whether a 12-week strength training program can help slow down early aging in 40 young adults (ages 18-35) who have had a first episode of psychosis. Researchers will measure telomere length (a marker of cellular aging) and other health indicators. The goal is…
Matched conditions: FIRST EPISODE PSYCHOSIS (FEP)
Sponsor: University of Salamanca • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Can a phone app curb cannabis use in early psychosis?
Symptom relief Not yet recruitingResearchers are testing two mobile app-based programs, CHAMPS and iCanChange, for young adults with first-episode psychosis who use cannabis. CHAMPS targets safer use for people not looking to quit, while iCanChange supports those who want to reduce or stop. The trial compares ea…
Matched conditions: FIRST EPISODE PSYCHOSIS (FEP)
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Symptom relief
Last updated Sep 12, 2026 00:00 UTC
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Breathing your way to better mental health: new app trial for psychosis
Symptom relief Not yet recruitingThis study tests a 5-week digital breathing program (heart rate variability biofeedback) to see if it improves well-being in people with first episode psychosis. 80 participants will either do the breathing exercises or listen to music. The goal is to reduce symptoms like depress…
Matched conditions: FIRST EPISODE PSYCHOSIS (FEP)
Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Could a nasal insulin spray rewire the brain in psychosis?
Knowledge-focused Not yet recruitingThis study investigates how insulin delivered through the nose changes dopamine signaling and energy use in the brains of people with first-episode psychosis. Researchers will compare brain scans and chemical levels in 46 participants (patients and healthy volunteers) after recei…
Matched conditions: FIRST EPISODE PSYCHOSIS (FEP)
Sponsor: Medical University of Vienna • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC