EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Clinical trials for EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA explained in plain language.
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New cocktail of drugs and radiation takes on tough lung cancer
Disease control OngoingThis study is testing a combination of drugs and radiation for people with extensive-stage small cell lung cancer (ES-SCLC) who haven't been treated yet. The drugs include olaparib (which blocks cancer cells from repairing themselves), durvalumab (which helps the immune system at…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 23, 2026 11:59 UTC
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New combo aims to keep lung cancer in check
Disease control OngoingThis phase II trial tests whether adding talazoparib to atezolizumab maintenance therapy works better than atezolizumab alone for people with a specific genetic marker (SLFN11-positive) and extensive-stage small cell lung cancer. About 100 participants will receive either the com…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 22, 2026 11:58 UTC
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Triple-Drug attack on tough lung cancer shows early promise
Disease control OngoingThis early-phase trial tests a combination of three drugs—tazemetostat, topotecan, and pembrolizumab—in adults with small cell lung cancer that has returned after initial treatment. The goal is to find the safest dose and see if the combo can shrink or stabilize the cancer. About…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 18, 2026 11:48 UTC
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New drug combo shows promise in slowing lung cancer return
Disease control OngoingThis study tests whether adding berzosertib to standard chemotherapy (topotecan) helps people with relapsed small cell lung cancer live longer without their cancer growing. About 104 participants will receive either the combination or topotecan alone. The goal is to see if blocki…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 12:55 UTC
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Triple-Drug cocktail shows promise for tough lung cancers
Disease control OngoingThis study tests a combination of three drugs (niraparib, temozolomide, and atezolizumab) in people with advanced solid tumors or extensive-stage small cell lung cancer that has responded to initial chemotherapy. The goal is to find the safest dose and see if the combination help…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:08 UTC
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Brain radiation may be skipped in lung cancer: new trial tests safer monitoring
Disease control OngoingThis study tests whether using MRI brain scans alone to watch for cancer spread is as good as combining MRI with preventive brain radiation in people with small cell lung cancer. The goal is to see if avoiding radiation can reduce side effects and help patients live longer. About…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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New combo aims to boost chemo for tough lung cancer
Disease control OngoingThis early-stage trial tests a new drug called LB-100 combined with standard chemotherapy and immunotherapy for people with untreated extensive-stage small cell lung cancer. The goal is to find the safest dose and see how well the combination works. Only 3 participants were enrol…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 01, 2026 17:58 UTC