Esophageal neoplasms
Clinical trials for Esophageal neoplasms explained in plain language.
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Common painkiller may boost Chemo's power against cancer
Disease control CompletedThis early-phase study tested whether adding indomethacin, a common anti-inflammatory drug, to standard platinum-based chemotherapy is safe for people with colorectal, esophageal, or ovarian cancers. The 13 participants received escalating doses of indomethacin alongside their ch…
Matched conditions: ESOPHAGEAL NEOPLASMS
Phase 1 • Sponsor: UMC Utrecht • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New drug cocktail plus radiation shows promise against esophageal cancer
Disease control CompletedThis phase II trial tested a combination of two chemotherapy drugs, cisplatin and irinotecan, given weekly along with radiation therapy for patients with locally advanced esophageal cancer. The study enrolled 43 participants and aimed to see how many had no detectable tumor after…
Matched conditions: ESOPHAGEAL NEOPLASMS
Phase 2 • Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Which chemo works best for esophageal cancer? new trial aims to find out
Disease control CompletedThis study compared two chemotherapy regimens (FOLFOX and CarboP-pacliT) given with radiation before surgery for esophageal or junction cancer. 106 patients were enrolled to see which treatment leads to better tumor removal and fewer serious complications. The goal is to help doc…
Matched conditions: ESOPHAGEAL NEOPLASMS
Phase 2 • Sponsor: Centre Oscar Lambret • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New scan could predict who benefits from esophageal cancer therapy
Knowledge-focused CompletedThis study explores whether a special PET/MRI scan can predict how well esophageal cancer responds to chemotherapy and radiation given before surgery. Researchers will scan 121 patients during treatment and compare the images with the actual tumor response seen after surgery. The…
Matched conditions: ESOPHAGEAL NEOPLASMS
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Sep 21, 2026 18:00 UTC
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Prehab before esophageal surgery: a feasibility test in older patients
Knowledge-focused CompletedThis study tested whether a program to improve physical fitness, nutrition, and sleep before surgery is possible for older adults with esophageal cancer. Fifteen patients aged 65 and older who had completed chemotherapy or radiotherapy took part. The goal was to see if patients w…
Matched conditions: ESOPHAGEAL NEOPLASMS
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC