ESOPHAGEAL ACHALASIA
Clinical trials for ESOPHAGEAL ACHALASIA explained in plain language.
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Routine acid pills after throat surgery: help or hype?
Disease control Recruiting nowThis study looks at whether taking acid-reducing medication (PPIs) every day for a year after a throat procedure called POEM is better than only taking it when symptoms appear. The goal is to prevent acid reflux and damage to the food pipe. About 132 adults with achalasia (a swal…
Matched conditions: ESOPHAGEAL ACHALASIA
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 26, 2026 11:51 UTC
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Botox or knife? new study tests simpler stomach drainage after esophageal cancer surgery
Symptom relief Recruiting nowThis study compares two ways to help the stomach empty properly after surgery to remove the esophagus (esophagectomy). One method uses Botox injections into the stomach valve, and the other is a surgical cut (pyloromyotomy). The goal is to see if Botox works as well as surgery at…
Matched conditions: ESOPHAGEAL ACHALASIA
Phase: PHASE2, PHASE3 • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated May 26, 2026 11:58 UTC
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Which POEM technique works best for swallowing trouble?
Symptom relief Recruiting nowThis study compares two versions of a procedure called POEM for people with achalasia, a condition where the esophagus doesn't relax properly, making swallowing difficult. About 52 adults will be randomly assigned to get either the standard circular muscle cut or a full-thickness…
Matched conditions: ESOPHAGEAL ACHALASIA
Phase: NA • Sponsor: Peking Union Medical College Hospital • Aim: Symptom relief
Last updated May 18, 2026 12:03 UTC
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Malnutrition may worsen surgery outcomes in achalasia patients
Knowledge-focused Recruiting nowThis study looks at how being malnourished affects breathing and kidney health in 60 adults with esophageal achalasia who are having a procedure called POEM. Researchers will measure carbon dioxide levels and kidney function during and after surgery. The goal is to understand if …
Matched conditions: ESOPHAGEAL ACHALASIA
Sponsor: Umraniye Education and Research Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 11:55 UTC
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Can a simple blood test predict esophageal cancer?
Knowledge-focused Recruiting nowThis study is collecting medical history, blood, and tissue samples from 7,000 people with esophageal disorders like GERD or Barrett's esophagus. Researchers hope to find genetic or protein markers that signal a higher risk of developing esophageal cancer. The goal is to enable e…
Matched conditions: ESOPHAGEAL ACHALASIA
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 26, 2026 11:54 UTC